clog-free filtersfor bioreactors
Clogging Kills Continuity
Membrane filters foul during runs, causing interruptions, yield loss, and emergency cleanups.
Impurities Compromise Safety
Residual Host Cell Proteins (HCPs) can escape membranes, reducing product purity and risking downstream compliance.
Downtime Costs Millions
Every cleaning cycle, membrane replacement, or run stoppage bleeds revenue, especially in high-throughput lines.
Benefits
- ultra-high cell density
- dead cell removal
- lower HCPs
- higher yield
- higher purity
Technology
inertial microfluidics
A mixed population enters the spiral unfocused. Inertial lift and Dean drag carry each cell to an equilibrium position set by its size: larger live cells to the inner wall, smaller dead cells and debris to the outer wall. A splitter at the core separates the two streams. No membrane, nothing to foul.
- Live cells
- inner wall → back to the bioreactor
- Dead cells & debris
- outer wall → waste
What We Stand ForInnovation. Precision. Performance.
At CelltoMix, we are redefining bioprocessing through next-generation microfluidic technology. Founded by leading scientists and engineers, our mission is to solve the industry's toughest filtration challenges, starting with clog-free, high-yield microfilters.
With a science-first approach and over two decades of international research experience behind our core team, we're building tools that increase cell culture productivity, reduce operational downtime, and optimize bioreactor performance.
We believe innovation in life sciences begins at the microscopic level, and that's exactly where we thrive.
Our TeamPrecision. Expertise. Global excellence.
Dr. Shireen Goh
scientific advisor & founder
Dr. Shireen Goh is scientific co-founder of Celltomix and Associate Professor at SUTD, specializing in microfluidics and biomanufacturing with technologies licensed to industry, including Erbi Biosystems (acquired by Merck in 2022).
The bench
- Dr. Danny van Noort
- Leo Siang Kwong
- Pranav Garg
- Siggy
50+ years of combined experience in technology, smart manufacturing, automation, microtechnology, bioengineering, physics and strategic marketing.
Dr. Danny van Noort
Co-Founder
Dr. Danny van Noort is an internationally recognized researcher with 25+ years of experience in physics, microtechnology, and biomedical engineering. He specializes in biosensors, DNA computers, organ-on-chips, and 3D cell models, with numerous publications and global lectures.
Leo Siang Kwong
Co-Founder
Leo Siang Kwong is an expert in digital transformation and automation, with 25+ years of experience in technology and engineering. A certified PMP and ScrumMaster, he specializes in leading large-scale digital initiatives, smart manufacturing, and ERP solutions, translating business vision into scalable innovation.
Siggy
Chief Morale Officer
Siggy supervises from above, contributes no code, and has never missed a standup that coincided with lunch.